Publications

In Press

Ho TC, Walker J, Teresi G, Kulla A, Kirshenbaum JS, Gifuni AJ, Singh MK, Gotlib IH (in press) Default mode and salience network alterations in suicidal and non-suicidal self-injurious thoughts and behaviors in adolescents with depression. Translational Psychiatry.

Ho TC, Sisk LM, Kulla A, Teresi GI, Hansen MM, Wu H, Gotlib IH (in press) Sex differences in myelin content of white matter tracts in adolescents with depression. Neuropsychopharmacology

Walker JC, Teresi GI, Weisenburger RL, Segarra JR, Ojha A, Kulla A, Sisk L, Gu M, Spielman DM, Rosenberg-Hasson Y, Maecker HT Singh MK, Gotlib IH, Ho TC (in press) Study protocol for Teen Inflammation Glutamate Emotion Research (TIGER). Frontiers in Human Neuroscience.

2021 Publications

Bickford, D, Morin, RT, Woodworth, C, Verduzco, E, Khan, M, Burns, E, Nelson, JC, & Mackin, RS (2021). The relationship of frailty and disability with suicidal ideation in late life depression. Aging & Mental Health, 25(3), 439-444. 

Christoffel DJ, Walsh JJ, Hoerbelt P, Heifets BD, Llorach P, Lopez RC, Ramakrishnan C, Deisseroth K, Malenka RC. Selective filtering of excitatory inputs to nucleus accumbens by dopamine and serotonin.  Proc Natl Acad Sci U S A. 2021 Jun 15;118(24).

Christoffel DJ, Walsh JJ, Heifets BD, Hoerbelt P, Neuner S, Sun G, Ravikumar VK, Wu H, Halpern CH, Malenka RC. Input-specific modulation of murine nucleus accumbens differentially regulates hedonic feeding. Nat Commun. 2021 Apr 9;12(1):2135.

Frank AC, Scangos KW, Larson PS, Norbu T, Lee AT, Lee AM (in press) Identification of a personalized intracranial biomarker of depression and response to DBS therapy. Brain Stimulationhttps://doi.org/10.1016/j.brs.2021.06.009

Frost NA, Haggart A, Sohal VS. Dynamic patterns of correlated activity in the prefrontal cortex encode information about social behavior. PLoS Biol. 2021 05; 19(5):e3001235. 

Ho TC, Teresi GI, Segarra JR, Ojha A, Walker JC, Gu M, Spielman DM, Sacchet MD, Jiang F, Rosenberg-Hasson Y, Maecker H (2021) Higher levels of pro-inflammatory cytokines are associated with higher levels of glutamate in the anterior cingulate cortex in depressed adolescents. Frontiers in Psychiatry. 1;12.

Ho TC, Gifuni AJ, Gotlib IH (2021) Psychobiological risk factors for suicidal thoughts and behaviors in adolescence: a consideration of the role of puberty. Molecular Psychiatry. Jun 11:1-8. doi: 10.1038/s41380-021-01171-5. 

Insel PS, Mohlenhoff BS, Neylan TC, Krystal AD, Mackin RS. Association of Sleep and β-Amyloid Pathology Among Older Cognitively Unimpaired Adults. JAMA Netw Open. 2021 Jul 01; 4(7):e2117573.  

Lutz, J, Mackin, RS, Otero, MC, Morin, R, Bickford, D, Tosun, D, Satre, DD, Gould, CE, Nelson, JC, Beaudreau, SA (2021). Improvements in Functional Disability After Psychotherapy for Depression Are Associated With Reduced Suicide Ideation Among Older Adults. American Journal of Geriatric Psychiatry, 9(6), 557-561. 

Mackin RS, Rhodes E, Insel PS, Nosheny R, Finley S, Ashford M, Camacho MR, Truran D, Mosca K, Seabrook G, Morrison R, Narayan VA, Weiner M. Reliability and Validity of a Home-Based Self-Administered Computerized Test of Learning and Memory Using Speech Recognition. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2021 Jun 17; 1-15.  

Mackin, RS, Insel, PS, Landau, S, Bickford, D, Morin, R, Rhodes, E, Tosun, D, Rosen, HJ, Butters, M, Aisen, P, Raman, R, Saykin, A, Toga, A, Jack, C, Koeppe, R, Weiner, M, & Nelson, C (2021). Late Life Depression is associated with Reduced Cortical Amyloid Burden: Findings from the ADNI Depression Project. Biological Psychiatry 89(8) 757-765. 

Ohayon MM, McCue M, Krystal A, Chrones L, Touya M, Lawrence D, Patel S, Cote ML. A Longitudinal Study to Assess Antidepressant Treatment Patterns and Outcomes in Individuals with Depression in the General Population. CNS Spectr. 2021 04; 26(2):180. 

Rhodes, E, Insel, P, Butters, M, Morin, R, Bickford, D, Tosun, D, Gessert, D, Rosen, H, Aisen, P, Raman, R, Landau, S, Saykin, A, Toga, A, Jack, C, Weiner, MW, Nelson, C, & Mackin, RS, on behalf of the Alzheimer’s Disease Neuroimaging Initiative & the ADNI Depression Project (2021). The Impact of Amyloid Burden and APOE on Rates of Cognitive Impairment in Late Life Depression. Journal of Alzheimer’s Disease 80(3), 991-1002. 

Scangos KW, Khambhati AN, Daly PM, Makhoul GS, Sugrue LP, Zamanian H, Liu TX, Rao VR, Sellers KK, Dawes HE, Starr PA, Krystal AD, Chang EF. Closed-loop neuromodulation in an individual with treatment-resistant depressionNature Medicine. 2021 Oct;27(10):1696-1700.

Scangos KW, Makhoul GS, Sugrue LP, Chang EF, Krystal AD. State-Dependent Responses to Intracranial Brain Stimulation in Depression:  A Case Report.  Nature Medicine 27196–197 (2021).

Scangos KW, Khambhati AN, Daly PM, Owen LW, Manning JR, Ambrose JB, Austin E, Dawes HE, Krystal AD, Chang EF. Distributed Subnetworks of Depression Defined by Direct Intracranial Neurophysiology. Front Hum Neurosci. 2021; 15:746499. 

Smith, M, Asada, N, Malenka, R Anterior cingulate inputs to neucleus accumbens control the social transfer of pain and analgesia. Science 371 (6525) 153-159. 

Steinberg EE, Gore F, Heifets BD, Taylor MD, Norville ZC, Beier KT, Földy C, Lerner TN, Luo L, Deisseroth K, Malenka RCAmygdala-Midbrain Connections Modulate Appetitive and Aversive Learning.  Neuron. 2020 Jun 17;106(6):1026-1043.e9. 

Vedam-Mai V, Deisseroth K, Giordano J, Lazaro-Munoz G, Chiong W, Suthana N, Langevin JP, Gill J, Goodman W, Provenza NR, Halpern CH, Shivacharan RS, Cunningham TN, Sheth SA, Pouratian N, Scangos KW, Mayberg HS, Horn A, Johnson KA, Butson CR, Gilron R, de Hemptinne C, Wilt R, Yaroshinsky M, Little S, Starr P, Worrell G, Shirvalkar P, Chang E, Volkmann J, Muthuraman M, Groppa S, Kühn AA, Li L, Johnson M, Otto KJ, Raike R, Goetz S, Wu C, Silburn P, Cheeran B, Pathak YJ, Malekmohammadi M, Gunduz A, Wong JK, Cernera S, Hu W, Wagle Shukla A, Ramirez-Zamora A, Deeb W, Patterson A, Foote KD, Okun MS. Corrigendum: Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies. Front Hum Neurosci. 2021; 15:765150. 

Vesuna S, Kauvar IV, Richman E, Gore F, Oskotsky T, Sava-Segal C, Luo L, Malenka RC, Henderson JM, Nuyujukian P, Parvizi J, Deisseroth K. Deep posteromedial cortical rhythm in dissociation. Nature. 2020 Oct;586(7827):87-94.

2020 Publications

Gergues MM, Han KJ, Choi HS ,Brown B, Clausing KJ,  Turner VS, Vainchtein ID, Molofsky AV, Kheirbek MA Circuit and molecular architecture of a ventral hippocampal network. Nature Neuroscience 2020

Ho TC, Gutman B, ENIGMA MDD Working Group, Sämann P, Schmaal L (2020) Subcortical shape alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder Working Group. Human Brain Mapping.

Mackin, RS, Insel, PS, Landau, S, Bickford, D, Morin, R, Rhodes, E, Tosun, D, Rosen, HJ, Butters, M, Aisen, P, Raman, R, Saykin, A, Toga, A, Jack, C, Koeppe, R, Weiner, M, & Nelson, C (2020). Late Life Depression is associated with Reduced Cortical Amyloid Burden: Findings from the ADNI Depression Project. Biological Psychiatry. 

Steinberg EE, Gore F, Heifets BD, Taylor MD, Norville ZC, Beier KT, Földy C, Lerner TN, Luo L, Deisseroth K, Malenka RC. Amygdala-Midbrain Connections Modulate Appetitive and Aversive Learning. Neuron. 2020 Jun 17;106(6):1026-1043.e9. doi: 10.1016/j.neuron.2020.03.016. Epub 2020 Apr 14.

Vesuna S, Kauvar IV, Richman E, Gore F, Oskotsky T, Sava-Segal C, Luo L, Malenka RC, Henderson JM, Nuyujukian P, Parvizi J, Deisseroth K. Deep posteromedial cortical rhythm in dissociation. Nature. 2020 Oct;586(7827):87-94. doi: 10.1038/s41586-020-2731-9. Epub 2020 Sep 16. PMID: 32939091 Free PMC article.

Xia F, Kheirbek MA. Circuit-based biomarkers for mood and anxiety disorders. Trends in Neurosciences 2020

2019 Publications

Scangos KW, Ahmad HS, Shafi A, Sellers KK, Dawes HE, Krystal A, Chang EF. Pilot Study of An Intracranial Electroencephalography Biomarker of Depressive Symptoms in Epilepsy.  J Neuropsychiatry Clin Neurosci. 2020 Spring;32(2):185-190. doi: 10.1176/appi.neuropsych.19030081. Epub 2019 Aug 9. PMID: 31394989

Scangos KW, Weiner RD, Coffey EC, Krystal AD. An Electrophysiological Biomarker That May Predict Treatment Response to ECT. J ECT. 2019 Jun;35(2):95-102. doi: 10.1097/YCT.0000000000000557. PMID: 30531398