Scott Mackin, PhD

PROF IN RES-HCOMP
Psychiatry
+1 415 476-7067
Publications: 

Characterizing Heterogeneity in Neuroimaging, Cognition, Clinical Symptoms, and Genetics Among Patients With Late-Life Depression.

JAMA psychiatry

Wen J, Fu CHY, Tosun D, Veturi Y, Yang Z, Abdulkadir A, Mamourian E, Srinivasan D, Skampardoni I, Singh A, Nawani H, Bao J, Erus G, Shou H, Habes M, Doshi J, Varol E, Mackin RS, Sotiras A, Fan Y, Saykin AJ, Sheline YI, Shen L, Ritchie MD, Wolk DA, Albert M, Resnick SM, Davatzikos C, iSTAGING consortium, ADNI, BIOCARD, and BLSA

Self-reporting of psychiatric illness in an online patient registry is a good indicator of the existence of psychiatric illness.

Journal of psychiatric research

Sordo Vieira L, Nguyen B, Nutley SK, Bertolace L, Ordway A, Simpson H, Zakrzewski J, Jean Gilles ME, Nosheny R, Weiner M, Mackin RS, Mathews CA

Health-related quality of life in hoarding: A comparison to chronic conditions with high disease burden.

Journal of psychiatric research

Nutley SK, Read M, Eichenbaum J, Nosheny RL, Weiner M, Mackin RS, Mathews CA

Remote blood collection from older adults in the Brain Health Registry for plasma biomarker and genetic analysis.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Fockler J, Ashford MT, Eichenbaum J, Howell T, Ekanem A, Flenniken D, Happ A, Truran D, Mackin RS, Blennow K, Halperin E, Coppola G, Weiner MW, Nosheny RL

Cognitive profile of people with mild behavioral impairment in Brain Health Registry participants.

International psychogeriatrics

Kassam F, Chen H, Nosheny RL, McGirr A, Williams T, Ng N, Camacho M, Mackin RS, Weiner MW, Ismail Z

Association of Sleep and ß-Amyloid Pathology Among Older Cognitively Unimpaired Adults.

JAMA network open

Insel PS, Mohlenhoff BS, Neylan TC, Krystal AD, Mackin RS

Home-Based Self-Administration of a Computerized Cognitive Tests of List Learning and Memory using Speech Recognition.

Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition

Mackin RS, Rhodes E, Insel PS, Nosheny R, Finley S, Ashford M, Camacho MR, Truran D, Seabrook K, Morrison G, Narayan R, Weiner V, Michael

Machine learning approaches to predicting amyloid status using data from an online research and recruitment registry: The Brain Health Registry.

Alzheimer's & dementia (Amsterdam, Netherlands)

Albright J, Ashford MT, Jin C, Neuhaus J, Rabinovici GD, Truran D, Maruff P, Mackin RS, Nosheny RL, Weiner MW

Brain health registry GenePool study: A novel approach to online genetics research.

Alzheimer's & dementia (New York, N. Y.)

Fockler J, Kwang W, Ashford MT, Flenniken D, Hwang J, Truran D, Mackin RS, Jin C, O'Hara R, Hallmayer JF, Yesavage JA, Weiner MW, Nosheny RL

Association of Midlife Depressive Symptoms with Regional Amyloid-ß and Tau in the Framingham Heart Study.

Journal of Alzheimer's disease : JAD

Gonzales MM, Samra J, O'Donnell A, Mackin RS, Salinas J, Jacob M, Satizabal CL, Aparicio HJ, Thibault EG, Sanchez JS, Finney R, Rubinstein ZB, Mayblyum DV, Killiany RJ, Decarli CS, Johnson KA, Beiser AS, Seshadri S

Hoarding disorder is associated with self-reported cardiovascular / metabolic dysfunction, chronic pain, and sleep apnea.

Journal of psychiatric research

Nutley SK, Camacho MR, Eichenbaum J, Nosheny RL, Weiner M, Delucchi KL, Mackin RS, Mathews CA

Reply to: Brain Amyloid Deposition in Late-Life Depression.

Biological psychiatry

Mackin RS, Insel PS

Internet-based hoarding assessment: The reliability and predictive validity of the internet-based Hoarding Rating Scale, Self-Report.

Psychiatry research

Nutley SK, Bertolace L, Vieira LS, Nguyen B, Ordway A, Simpson H, Zakrzewski J, Camacho MR, Eichenbaum J, Nosheny R, Weiner M, Mackin RS, Mathews CA

Improvements in Functional Disability After Psychotherapy for Depression Are Associated With Reduced Suicide Ideation Among Older Adults.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Lutz J, Mackin RS, Otero MC, Morin R, Bickford D, Tosun D, Satre DD, Gould CE, Nelson JC, Beaudreau SA

Predicting amyloid status using self-report information from an online research and recruitment registry: The Brain Health Registry.

Alzheimer's & dementia (Amsterdam, Netherlands)

Ashford MT, Neuhaus J, Jin C, Camacho MR, Fockler J, Truran D, Mackin RS, Rabinovici GD, Weiner MW, Nosheny RL

Validation of online functional measures in cognitively impaired older adults.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Nosheny RL, Camacho MR, Jin C, Neuhaus J, Truran D, Flenniken D, Ashford M, Carrillo MC, Fargo KN, Hendrix J, Hanna L, Rabinovici G, Maruff P, Mackin RS, Weiner MW

Late-Life Depression Is Associated With Reduced Cortical Amyloid Burden: Findings From the Alzheimer's Disease Neuroimaging Initiative Depression Project.

Biological psychiatry

Mackin RS, Insel PS, Landau S, Bickford D, Morin R, Rhodes E, Tosun D, Rosen HJ, Butters M, Aisen P, Raman R, Saykin A, Toga A, Jack C, Koeppe R, Weiner MW, Nelson C

Effects of sex, race, ethnicity, and education on online aging research participation.

Alzheimer's & dementia (New York, N. Y.)

Ashford MT, Eichenbaum J, Williams T, Camacho MR, Fockler J, Ulbricht A, Flenniken D, Truran D, Mackin RS, Weiner MW, Nosheny RL

Visually mediated functioning improves following treatment of hoarding disorder.

Journal of affective disorders

J Zakrzewski J, A Gillett D, R Vigil O, C Smith L, Komaiko K, Chou CY, Y Uhm S, Bain LD, J Stark S, Gause M, Howell G, Vega E, Chan J, B Eckfield M, Y Tsoh J, Delucchi K, Mackin RS, A Mathews C

The relationship of frailty and disability with suicidal ideation in late life depression.

Aging & mental health

Bickford D, Morin RT, Woodworth C, Verduzco E, Khan M, Burns E, Nelson JC, Mackin RS

Study partner-reported decline identifies cognitive decline and dementia risk.

Annals of clinical and translational neurology

Nosheny RL, Jin C, Neuhaus J, Insel PS, Mackin RS, Weiner MW

Comorbidity Profiles Identified in Older Primary Care Patients Who Attempt Suicide.

Journal of the American Geriatrics Society

Morin RT, Li Y, Mackin RS, Whooley MA, Conwell Y, Byers AL

Impaired Financial Capacity in Late-Life Depression: Revisiting Associations with Cognitive Functioning.

Journal of the International Neuropsychological Society : JINS

Morin RT, Gonzales MM, Bickford D, Catalinotto D, Nelson C, Mackin RS

Determining clinically meaningful decline in preclinical Alzheimer disease.

Neurology

Insel PS, Weiner M, Mackin RS, Mormino E, Lim YY, Stomrud E, Palmqvist S, Masters CL, Maruff PT, Hansson O, Mattsson N

Latent Classes of Cognitive Functioning Among Depressed Older Adults Without Dementia.

Journal of the International Neuropsychological Society : JINS

Morin RT, Insel P, Nelson C, Butters M, Bickford D, Landau S, Saykin A, Weiner M, Mackin RS

Somatic and anxiety symptoms of depression are associated with disability in late life depression.

Aging & mental health

Morin RT, Nelson C, Bickford D, Insel PS, Mackin RS

Cognitive Performance in Parkinson's Disease in the Brain Health Registry.

Journal of Alzheimer's disease : JAD

Cholerton B, Weiner MW, Nosheny RL, Poston KL, Mackin RS, Tian L, Ashford JW, Montine TJ

Online study partner-reported cognitive decline in the Brain Health Registry.

Alzheimer's & dementia (New York, N. Y.)

Nosheny RL, Camacho MR, Insel PS, Flenniken D, Fockler J, Truran D, Finley S, Ulbricht A, Maruff P, Yaffe K, Mackin RS, Weiner MW

Total Sleep Time Interacts With Age to Predict Cognitive Performance Among Adults.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Mohlenhoff BS, Insel PS, Mackin RS, Neylan TC, Flenniken D, Nosheny R, Richards A, Maruff P, Weiner MW

Randomised clinical trial of community-based peer-led and psychologist-led group treatment for hoarding disorder.

BJPsych open

Mathews CA, Mackin RS, Chou CY, Uhm SY, Bain LD, Stark SJ, Gause M, Vigil OR, Franklin J, Salazar M, Plumadore J, Smith LC, Komaiko K, Howell G, Vega E, Chan J, Eckfield MB, Tsoh JY, Delucchi K

Chronic depressive symptomatology and CSF amyloid beta and tau levels in mild cognitive impairment.

International journal of geriatric psychiatry

Gonzales MM, Insel PS, Nelson C, Tosun D, Schöll M, Mattsson N, Sacuiu S, Bickford D, Weiner MW, Mackin RS

Screening for Executive Dysfunction in Late-Life Depression: Utility of Trail Making Test and Self-Report Measures.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Bickford D, Morin RT, Catalinotto D, Mackin RS, Nelson JC

Unsupervised online neuropsychological test performance for individuals with mild cognitive impairment and dementia: Results from the Brain Health Registry.

Alzheimer's & dementia (Amsterdam, Netherlands)

Mackin RS, Insel PS, Truran D, Finley S, Flenniken D, Nosheny R, Ulbright A, Comacho M, Bickford D, Harel B, Maruff P, Weiner MW

The Brain Health Registry: An internet-based platform for recruitment, assessment, and longitudinal monitoring of participants for neuroscience studies.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Weiner MW, Nosheny R, Camacho M, Truran-Sacrey D, Mackin RS, Flenniken D, Ulbricht A, Insel P, Finley S, Fockler J, Veitch D

Alcohol and Drug Use Among Older Adults: Associations with Widowhood, Relationship Quality, and Physical Health.

The journals of gerontology. Series B, Psychological sciences and social sciences

Satre DD, Bahorik AL, Mackin RS

Amyloid pathology in the progression to mild cognitive impairment.

Neurobiology of aging

Insel PS, Hansson O, Mackin RS, Weiner M, Mattsson N

?Cortical Atrophy is Associated with Accelerated Cognitive Decline in Mild Cognitive Impairment with Subsyndromal Depression.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Gonzales MM, Insel PS, Nelson C, Tosun D, Mattsson N, Mueller SG, Sacuiu S, Bickford D, Weiner MW, Mackin RS

Cognitive and functional changes associated with Aß pathology and the progression to mild cognitive impairment.

Neurobiology of aging

Insel PS, Donohue MC, Mackin RS, Aisen PS, Hansson O, Weiner MW, Mattsson N

Assessing risk for preclinical ß-amyloid pathology with APOE, cognitive, and demographic information.

Alzheimer's & dementia (Amsterdam, Netherlands)

Insel PS, Palmqvist S, Mackin RS, Nosheny RL, Hansson O, Weiner MW, Mattsson N

Comparison of a peer facilitated support group to cognitive behavior therapy: Study protocol for a randomized controlled trial for hoarding disorder.

Contemporary clinical trials

Uhm SY, Tsoh JY, Mackin RS, Gause M, Chan J, Franklin J, Eckfield M, Salazar M, Vigil O, Bain D, Stark S, Vega E, Delucchi KL, Mathews CA

Accelerating rates of cognitive decline and imaging markers associated with ß-amyloid pathology.

Neurology

Insel PS, Mattsson N, Mackin RS, Schöll M, Nosheny RL, Tosun D, Donohue MC, Aisen PS, Jagust WJ, Weiner MW

PATTERNS OF CLINICALLY SIGNIFICANT COGNITIVE IMPAIRMENT IN HOARDING DISORDER.

Depression and anxiety

Mackin RS, Vigil O, Insel P, Kivowitz A, Kupferman E, Hough CM, Fekri S, Crothers R, Bickford D, Delucchi KL, Mathews CA

Evidence for age-associated cognitive decline from Internet game scores.

Alzheimer's & dementia (Amsterdam, Netherlands)

Geyer J, Insel P, Farzin F, Sternberg D, Hardy JL, Scanlon M, Mungas D, Kramer J, Mackin RS, Weiner MW

Neuropsychological and dimensional behavioral trait profiles in Costa Rican ADHD sib pairs: Potential intermediate phenotypes for genetic studies.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics

Peskin VA, Ordóñez A, Mackin RS, Delucchi K, Monge S, McGough JJ, Chavira DA, Berrocal M, Cheung E, Fournier E, Badner JA, Herrera LD, Mathews CA

Chronic Depressive Symptomatology in Mild Cognitive Impairment Is Associated with Frontal Atrophy Rate which Hastens Conversion to Alzheimer Dementia.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Sacuiu S, Insel PS, Mueller S, Tosun D, Mattsson N, Jack CR, DeCarli C, Petersen R, Aisen PS, Weiner MW, Mackin RS

Biomarkers and cognitive endpoints to optimize trials in Alzheimer's disease.

Annals of clinical and translational neurology

Insel PS, Mattsson N, Mackin RS, Kornak J, Nosheny R, Tosun-Turgut D, Donohue MC, Aisen PS, Weiner MW

Cerebrospinal fluid a-synuclein and Lewy body-like symptoms in normal controls, mild cognitive impairment, and Alzheimer's disease.

Journal of Alzheimer's disease : JAD

Mackin RS, Insel P, Zhang J, Mohlenhoff B, Galasko D, Weiner M, Mattsson N

The transitional association between ß-amyloid pathology and regional brain atrophy.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Insel PS, Mattsson N, Donohue MC, Mackin RS, Aisen PS, Jack CR, Shaw LM, Trojanowski JQ, Weiner MW

Peripheral antioxidant markers are associated with total hippocampal and CA3/dentate gyrus volume in MDD and healthy controls-preliminary findings.

Psychiatry research

Lindqvist D, Mueller S, Mellon SH, Su Y, Epel ES, Reus VI, Rosser R, Mahan L, Mackin RS, Yang TT, Wolkowitz OM

Association of age at depression onset with cognitive functioning in individuals with late-life depression and executive dysfunction.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Mackin RS, Nelson JC, Delucchi KL, Raue PJ, Satre DD, Kiosses DN, Alexopoulos GS, Arean PA

Neuroimaging abnormalities in adults with sickle cell anemia: associations with cognition.

Neurology

Mackin RS, Insel P, Truran D, Vichinsky EP, Neumayr LD, Armstrong FD, Gold JI, Kesler K, Brewer J, Weiner MW

Cognitive outcomes after psychotherapeutic interventions for major depression in older adults with executive dysfunction.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Mackin RS, Nelson JC, Delucchi K, Raue P, Byers A, Barnes D, Satre DD, Yaffe K, Alexopoulos GS, Arean PA

Patterns of reduced cortical thickness in late-life depression and relationship to psychotherapeutic response.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Mackin RS, Tosun D, Mueller SG, Lee JY, Insel P, Schuff N, Truran-Sacrey D, Arean P, Nelson JC, Weiner MW

The effect of subsyndromal symptoms of depression and white matter lesions on disability for individuals with mild cognitive impairment.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Mackin RS, Insel P, Tosun D, Mueller SG, Schuff N, Truran-Sacrey D, Raptentsetsang ST, Lee JY, Jack CR, Aisen PS, Petersen RC, Weiner MW

A composite score for executive functioning, validated in Alzheimer's Disease Neuroimaging Initiative (ADNI) participants with baseline mild cognitive impairment.

Brain imaging and behavior

Gibbons LE, Carle AC, Mackin RS, Harvey D, Mukherjee S, Insel P, Curtis SM, Mungas D, Crane PK

Development and assessment of a composite score for memory in the Alzheimer's Disease Neuroimaging Initiative (ADNI).

Brain imaging and behavior

Crane PK, Carle A, Gibbons LE, Insel P, Mackin RS, Gross A, Jones RN, Mukherjee S, Curtis SM, Harvey D, Weiner M, Mungas D

Dysexecutive and amnesic AD subtypes defined by single indicator and modern psychometric approaches: relationships with SNPs in ADNI.

Brain imaging and behavior

Mukherjee S, Trittschuh E, Gibbons LE, Mackin RS, Saykin A, Crane PK

Different associations of white matter lesions with depression and cognition.

BMC neurology

Lee JY, Insel P, Mackin RS, Schuff N, Chui H, DeCarli C, Park KH, Mueller SG, Weiner MW

Plasma biomarkers of depressive symptoms in older adults.

Translational psychiatry

Arnold SE, Xie SX, Leung YY, Wang LS, Kling MA, Han X, Kim EJ, Wolk DA, Bennett DA, Chen-Plotkin A, Grossman M, Hu W, Lee VM, Mackin RS, Trojanowski JQ, Wilson RS, Shaw LM

Patterns of alcohol and drug use among depressed older adults seeking outpatient psychiatric services.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Satre DD, Sterling SA, Mackin RS, Weisner C

Differentiating illiteracy from Alzheimer's disease by using neuropsychological assessments.

International psychogeriatrics

Youn JH, Siksou M, Mackin RS, Choi JS, Chey J, Lee JY

The effect of cognitive impairment on mental healthcare costs for individuals with severe psychiatric illness.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Mackin RS, Delucchi KL, Bennett RW, Areán PA

Problem-solving therapy and supportive therapy in older adults with major depression and executive dysfunction: effect on disability.

Archives of general psychiatry

Alexopoulos GS, Raue PJ, Kiosses DN, Mackin RS, Kanellopoulos D, McCulloch C, Areán PA

Cognitive functioning in individuals with severe compulsive hoarding behaviors and late life depression.

International journal of geriatric psychiatry

Mackin RS, Areán PA, Delucchi KL, Mathews CA

Recruitment of African Americans and Asian Americans with late-life depression and mild cognitive impairment.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Bistricky SL, Mackin RS, Chu JP, Areán PA

Problem-solving therapy and supportive therapy in older adults with major depression and executive dysfunction.

The American journal of psychiatry

Areán PA, Raue P, Mackin RS, Kanellopoulos D, McCulloch C, Alexopoulos GS

Incidence and documentation of cognitive impairment among older adults with severe mental illness in a community mental health setting.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Mackin RS, Areán PA

Evidence-based psychotherapeutic interventions for geriatric depression.

The Psychiatric clinics of North America

Mackin RS, Areán PA

Neuropsychological test performance prior to and following sports-related mild traumatic brain injury.

Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine

Echemendia RJ, Putukian M, Mackin RS, Julian L, Shoss N