Tiffany Ho, PhD

Assistant Adjunct Professor
Psychiatry

Dr. Ho is a cognitive neuroscientist with expertise in non-invasive MR imaging and training in affective science and developmental psychology. Dr. Ho's research program focuses on how stress-related changes in key neural circuits during sensitive periods of development contribute to depression risk and other related conditions. The primary goal of Dr. Ho's research program is to inform the development and refinement of interventions aimed at treating or preventing depression in adolescents, including identifying who may achieve the most gains from existing treatments based on their psychobiological profiles.

Current projects in the lab include:

(1) Characterizing the biobehavioral mechanisms by which experiences of early adversity and perceptions of stress influence brain phenotypes and neurodevelopmental trajectories in adolescents

(2) Understanding the confluence of inflammation and glutamate on neural circuitry, symptom progression, and treatment response in depressed adolescents

(3) Elucidating the roles of pubertal hormones on susceptibility to stress, mood dynamics, and longer term neurodevelopment

(4) Identifying multi-level predictors of depression and suicidal thoughts and predictors in adolescents using machine learning analytics

(5) Generating neuroscientifically validated digital phenotypes of mood (i.e., scalable biomarkers) in collaboration with Dr. Nicholas Allen at the University of Oregon / Ksana Health

(6) Conducting harmonized meta-analytic investigations on the effects of stress and depression on brain morphometry in collaboration with ENIGMA

Publications: 

Multi-site benchmark classification of major depressive disorder using machine learning on cortical and subcortical measures.

Scientific reports

Belov V, Erwin-Grabner T, Aghajani M, Aleman A, Amod AR, Basgoze Z, Benedetti F, Besteher B, Bülow R, Ching CRK, Connolly CG, Cullen K, Davey CG, Dima D, Dols A, Evans JW, Fu CHY, Gonul AS, Gotlib IH, Grabe HJ, Groenewold N, Hamilton JP, Harrison BJ, Ho TC, Mwangi B, Jaworska N, Jahanshad N, Klimes-Dougan B, Koopowitz SM, Lancaster T, Li M, Linden DEJ, MacMaster FP, Mehler DMA, Melloni E, Mueller BA, Ojha A, Oudega ML, Penninx BWJH, Poletti S, Pomarol-Clotet E, Portella MJ, Pozzi E, Reneman L, Sacchet MD, Sämann PG, Schrantee A, Sim K, Soares JC, Stein DJ, Thomopoulos SI, Uyar-Demir A, van der Wee NJA, van der Werff SJA, Völzke H, Whittle S, Wittfeld K, Wright MJ, Wu MJ, Yang TT, Zarate C, Veltman DJ, Schmaal L, Thompson PM, Goya-Maldonado R, ENIGMA Major Depressive Disorder working group

Exploring sex differences in trajectories of pubertal development and mental health following early adversity.

Psychoneuroendocrinology

Ho TC, Buthmann J, Chahal R, Miller JG, Gotlib IH

Protocol for teen inflammation glutamate emotion research (TIGER): Toward predictors of treatment response and clinical course in depressed adolescents.

Brain, behavior, & immunity - health

Coury SM, López V, Bajwa Z, Garcia JM, Teresi GI, Kuhlman KR, Li Y, Cole S, Miklowitz DJ, Pappas I, Ho TC

Neighborhood Socioeconomic Disadvantage and White Matter Microstructure of the Arcuate Fasciculus and Uncinate Fasciculus in Adolescents.

Biological psychiatry global open science

Kulla A, Coury S, Garcia JM, Teresi GI, Sisk LM, Hansen M, Miller JG, Gotlib IH, Ho TC

Preparation and processing of dried blood spots for microRNA sequencing.

Biology methods & protocols

Morgunova A, Ibrahim P, Chen GG, Coury SM, Turecki G, Meaney MJ, Gifuni A, Gotlib IH, Nagy C, Ho TC, Flores C

Early life stress, sleep disturbances, and depressive symptoms during adolescence: The role of the cingulum bundle.

Developmental cognitive neuroscience

Uy JP, Ho TC, Buthmann JL, Coury SM, Gotlib IH

Early life stress moderates the relation between systemic inflammation and neural activation to reward in adolescents both cross-sectionally and longitudinally.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Yuan JP, Coury SM, Ho TC, Gotlib IH

Subcortical Brain Alterations in Carriers of Genomic Copy Number Variants.

The American journal of psychiatry

Kumar K, Modenato C, Moreau C, Ching CRK, Harvey A, Martin-Brevet S, Huguet G, Jean-Louis M, Douard E, Martin CO, Younis N, Tamer P, Maillard AM, Rodriguez-Herreros B, Pain A, 16p11.2 European Consortium, Simons Searchlight Consortium, Kushan L, Isaev D, Alpert K, Ragothaman A, Turner JA, Wang L, Ho TC, Schmaal L, Silva AI, van den Bree MBM, Linden DEJ, Owen MJ, Hall J, Lippé S, Dumas G, Draganski B, Gutman BA, Sønderby IE, Andreassen OA, Schultz LM, Almasy L, Glahn DC, Bearden CE, Thompson PM, Jacquemont S

How Obstructed Action Efficacy Impacts Reward-based Decision-making in Adolescent Depression: An fMRI Study.

Journal of the American Academy of Child and Adolescent Psychiatry

Harl? KM, Ho TC, Connolly CG, Simmons A, Yang TT

Transcutaneous retrobulbar amphotericin B for rhino-orbital-cerebral mucormycosis: a multi-center retrospective comparative study.

Orbit (Amsterdam, Netherlands)

Dallalzadeh LO, Ediriwickrema LS, Fung SE, Men CJ, Kossler AL, Kupcha AC, Mawn LA, Burkat CN, van Landingham SW, Conger JR, Simmons B, Pham C, Akella SS, Setabutr P, Ho T, Couch SM, Kim JS, Demirci H, Korn BS, Kikkawa DO, Liu CY

Concurrent validity and reliability of suicide risk assessment instruments: A meta-analysis of 20 instruments across 27 international cohorts.

Neuropsychology

Campos AI, Van Velzen LS, Veltman DJ, Pozzi E, Ambrogi S, Ballard ED, Banaj N, Basg?ze Z, Bellow S, Benedetti F, Bollettini I, Brosch K, Canales-Rodr?guez EJ, Clarke-Rubright EK, Colic L, Connolly CG, Courtet P, Cullen KR, Dannlowski U, Dauvermann MR, Davey CG, Deverdun J, Dohm K, Erwin-Grabner T, Goya-Maldonado R, Fani N, Fortea L, Fuentes-Claramonte P, Gonul AS, Gotlib IH, Grotegerd D, Harris MA, Harrison BJ, Haswell CC, Hawkins EL, Hill D, Hirano Y, Ho TC, Jollant F, Jovanovic T, Kircher T, Klimes-Dougan B, le Bars E, Lochner C, McIntosh AM, Meinert S, Mekawi Y, Melloni E, Mitchell P, Morey RA, Nakagawa A, Nenadic I, Oli? E, Pereira F, Phillips RD, Piras F, Poletti S, Pomarol-Clotet E, Radua J, Ressler KJ, Roberts G, Rodriguez-Cano E, Sacchet MD, Salvador R, Sandu AL, Shimizu E, Singh A, Spalletta G, Steele JD, Stein DJ, Stein F, Stevens JS, Teresi GI, Uyar-Demir A, van der Wee NJ, van der Werff SJ, van Rooij SJH, Vecchio D, Verdolini N, Vieta E, Waiter GD, Whalley H, Whittle SL, Yang TT, Zarate CA, Thompson PM, Jahanshad N, van Harmelen AL, Blumberg HP, Schmaal L, Renter?a ME

Subcortical brain alterations in carriers of genomic copy number variants.

medRxiv : the preprint server for health sciences

Kumar K, Modenato C, Moreau C, Ching CRK, Harvey A, Martin-Brevet S, Huguet G, Jean-Louis M, Douard E, Martin CO, Younis N, Tamer P, Maillard AM, Rodriguez-Herreros B, Pain A, Richetin S, 16p11.2 European Consortium, Simons Searchlight Consortium, Kushan L, Isaev D, Alpert K, Ragothaman A, Turner JA, Wang L, Ho TC, Schmaal L, Silva AI, van den Bree MBM, Linden DEJ, Owen MJ, Hall J, Lipp? S, Dumas G, Draganski B, Gutman BA, S?nderby IE, Andreassen OA, Schultz L, Almasy L, Glahn DC, Bearden CE, Thompson PM, Jacquemont S

The effects of puberty and sex on adolescent white matter development: A systematic review.

Developmental cognitive neuroscience

Piekarski DJ, Colich NL, Ho TC

Effects of the COVID-19 Pandemic on Mental Health and Brain Maturation in Adolescents: Implications for Analyzing Longitudinal Data.

Biological psychiatry global open science

Gotlib IH, Miller JG, Borchers LR, Coury SM, Costello LA, Garcia JM, Ho TC

The gut microbiota, HPA axis, and brain in adolescent-onset depression: Probiotics as a novel treatment.

Brain, behavior, & immunity - health

Freimer D, Yang TT, Ho TC, Tymofiyeva O, Leung C

Outcomes of Patients With Thyroid Eye Disease Partially Treated With Teprotumumab.

Ophthalmic plastic and reconstructive surgery

Ho TC, Maamari RN, Kossler AL, Sears CM, Freitag SK, Reshef ER, Shinder R, Rootman DB, Diniz SB, Kahana A, Schlachter D, Do TH, Kally P, Turner S, Mokhtarzadeh A, Harrison AR, Hwang CJ, Kim HJ, Avila SA, Thomas DA, Magazin M, Wester ST, Lee WW, Clauss KD, Holds JB, Sniegowski M, Compton CJ, Briggs C, Malik AI, Lucarelli MJ, Burkat CN, Patel LG, Couch SM

Structural brain alterations associated with suicidal thoughts and behaviors in young people: results from 21 international studies from the ENIGMA Suicidal Thoughts and Behaviours consortium.

Molecular psychiatry

van Velzen LS, Dauvermann MR, Colic L, Villa LM, Savage HS, Toenders YJ, Zhu AH, Bright JK, Campos AI, Salminen LE, Ambrogi S, Ayesa-Arriola R, Banaj N, Basgöze Z, Bauer J, Blair K, Blair RJ, Brosch K, Cheng Y, Colle R, Connolly CG, Corruble E, Couvy-Duchesne B, Crespo-Facorro B, Cullen KR, Dannlowski U, Davey CG, Dohm K, Fullerton JM, Gonul AS, Gotlib IH, Grotegerd D, Hahn T, Harrison BJ, He M, Hickie IB, Ho TC, Iorfino F, Jansen A, Jollant F, Kircher T, Klimes-Dougan B, Klug M, Leehr EJ, Lippard ETC, McLaughlin KA, Meinert S, Miller AB, Mitchell PB, Mwangi B, Nenadic I, Ojha A, Overs BJ, Pfarr JK, Piras F, Ringwald KG, Roberts G, Romer G, Sanches M, Sheridan MA, Soares JC, Spalletta G, Stein F, Teresi GI, Tordesillas-Gutiérrez D, Uyar-Demir A, van der Wee NJA, van der Werff SJ, Vermeiren RRJM, Winter A, Wu MJ, Yang TT, Thompson PM, Rentería ME, Jahanshad N, Blumberg HP, van Harmelen AL, ENIGMA Suicidal Thoughts and Behaviours Consortium, Schmaal L

Patient and Provider Experience in Real-Time Telemedicine Consultations for Pediatric Ophthalmology.

Clinical ophthalmology (Auckland, N.Z.)

Stewart C, Coffey-Sandoval J, Souverein EA, Ho TC, Lee TC, Nallasamy S

Early life stress, systemic inflammation, and neural correlates of implicit emotion regulation in adolescents.

Brain, behavior, and immunity

Yuan JP, Ho TC, Coury SM, Chahal R, Colich NL, Gotlib IH

Longitudinal Change in Adolescent Depression and Anxiety Symptoms from before to during the COVID-19 Pandemic.

Journal of research on adolescence : the official journal of the Society for Research on Adolescence

Barendse MEA, Flannery J, Cavanagh C, Aristizabal M, Becker SP, Berger E, Breaux R, Campione-Barr N, Church JA, Crone EA, Dahl RE, Dennis-Tiwary TA, Dvorsky MR, Dziura SL, van de Groep S, Ho TC, Killoren SE, Langberg JM, Larguinho TL, Magis-Weinberg L, Michalska KJ, Mullins JL, Nadel H, Porter BM, Prinstein MJ, Redcay E, Rose AJ, Rote WM, Roy AK, Sweijen SW, Telzer EH, Teresi GI, Thomas AG, Pfeifer JH

Dimensions of Early Adversity and the Development of Functional Brain Network Connectivity During Adolescence: Implications for Trajectories of Internalizing Symptoms.

Biological psychiatry

Rajpreet Chahal, Jonas G. Miller, Justin P. Yuan, Jessica L. Buthmann, Tiffany C. Ho, Ian H. Gotlib

P348. Childhood Emotional Abuse is Associated with Delayed Brain Age in Depressed Adolescents.

Biological psychiatry

Vanessa Lopez, Miller G. Jonas, Ian H. Gotlib, Tiffany Ho

Predicting Depression Risk in Adolescents From Multimodal Data: Current Evidence and Future Directions.

Biological psychiatry. Cognitive neuroscience and neuroimaging

Ho TC

Multi-level predictors of depression symptoms in the Adolescent Brain Cognitive Development (ABCD) study.

Journal of child psychology and psychiatry, and allied disciplines

Ho TC, Shah R, Mishra J, May AC, Tapert SF

The effect of obstructed action efficacy on reward-based decision-making in healthy adolescents: a novel functional MRI task to assay frustration.

Cognitive, affective & behavioral neuroscience

Harlé KM, Ho TC, Connolly CG, Simmons AN, Yang TT

Inflammatory cytokines and callosal white matter microstructure in adolescents.

Brain, behavior, and immunity

Ho TC, Kulla A, Teresi GI, Sisk LM, Rosenberg-Hasson Y, Maecker HT, Gotlib IH

Correlates and predictors of the severity of suicidal ideation in adolescence: an examination of brain connectomics and psychosocial characteristics.

Journal of child psychology and psychiatry, and allied disciplines

Kirshenbaum JS, Chahal R, Ho TC, King LS, Gifuni AJ, Mastrovito D, Coury SM, Weisenburger RL, Gotlib IH

White Matter Microstructural Properties of the Cerebellar Peduncles Predict Change in Symptoms of Psychopathology in Adolescent Girls.

Cerebellum (London, England)

Borchers LR, Bruckert L, Chahal R, Mastrovito D, Ho TC, Gotlib IH

Sex differences in myelin content of white matter tracts in adolescents with depression.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Ho TC, Sisk LM, Kulla A, Teresi GI, Hansen MM, Wu H, Gotlib IH

Brain cortical and subcortical morphology in adolescents with depression and a history of suicide attempt.

Journal of psychiatry & neuroscience : JPN

Gifuni AJ, Chakravarty MM, Lepage M, Ho TC, Geoffroy MC, Lacourse E, Gotlib IH, Turecki G, Renaud J, Jollant F

Inflammatory Cytokines and Anterior Cingulate Cortex Glutamate in Adolescent Depression.

Biological psychiatry

Jillian Segarra, Giana Teresi, Meng Gu, Daniel Spielman, Matthew Sacchet, Yael Rosenberg-Hasson, Holden Maecker, Ian Gotlib, Tiffany Ho

Sensitivity to Life Stress, Amygdala-Based Functional Connectivity, and Internalizing Symptoms in Adolescents.

Biological psychiatry

Johanna Walker, Anthony Gifuni, Giana Teresi, Rachel Weisenburger, Jaclyn Kirshenbaum, Tiffany Ho, Ian Gotlib

Smartphone-Based Assessments of Negative Language Use, Central Executive Network Coherence, and Depression in Adolescents.

Biological psychiatry

Giana Teresi, Jillian Segarra, Jaclyn Kirshenbaum, Lauren Kahn, Nicholas Allen, Ian Gotlib, Tiffany Ho

ENIGMA-Sleep: Challenges, opportunities, and the road map.

Journal of sleep research

Tahmasian M, Aleman A, Andreassen OA, Arab Z, Baillet M, Benedetti F, Bresser T, Bright J, Chee MWL, Chylinski D, Cheng W, Deantoni M, Dresler M, Eickhoff SB, Eickhoff CR, Elvsåshagen T, Feng J, Foster-Dingley JC, Ganjgahi H, Grabe HJ, Groenewold NA, Ho TC, Bong Hong S, Houenou J, Irungu B, Jahanshad N, Khazaie H, Kim H, Koshmanova E, Kocevska D, Kochunov P, Lakbila-Kamal O, Leerssen J, Li M, Luik AI, Muto V, Narbutas J, Nilsonne G, O'Callaghan VS, Olsen A, Osorio RS, Poletti S, Poudel G, Reesen JE, Reneman L, Reyt M, Riemann D, Rosenzweig I, Rostampour M, Saberi A, Schiel J, Schmidt C, Schrantee A, Sciberras E, Silk TJ, Sim K, Smevik H, Soares JC, Spiegelhalder K, Stein DJ, Talwar P, Tamm S, Teresi GL, Valk SL, Van Someren E, Vandewalle G, Van Egroo M, Völzke H, Walter M, Wassing R, Weber FD, Weihs A, Westlye LT, Wright MJ, Wu MJ, Zak N, Zarei M

Higher Levels of Pro-inflammatory Cytokines Are Associated With Higher Levels of Glutamate in the Anterior Cingulate Cortex in Depressed Adolescents.

Frontiers in psychiatry

Ho TC, Teresi GI, Segarra JR, Ojha A, Walker JC, Gu M, Spielman DM, Sacchet MD, Jiang F, Rosenberg-Hasson Y, Maecker H, Gotlib IH

Brain Correlates of Suicide Attempt in 18,925 Participants Across 18 International Cohorts.

Biological psychiatry

Campos AI, Thompson PM, Veltman DJ, Pozzi E, van Veltzen LS, Jahanshad N, Adams MJ, Baune BT, Berger K, Brosch K, Bülow R, Connolly CG, Dannlowski U, Davey CG, de Zubicaray GI, Dima D, Erwin-Grabner T, Evans JW, Fu CHY, Gotlib IH, Goya-Maldonado R, Grabe HJ, Grotegerd D, Harris MA, Harrison BJ, Hatton SN, Hermesdorf M, Hickie IB, Ho TC, Kircher T, Krug A, Lagopoulos J, Lemke H, McMahon K, MacMaster FP, Martin NG, McIntosh AM, Medland SE, Meinert S, Meller T, Nenadic I, Opel N, Redlich R, Reneman L, Repple J, Sacchet MD, Schmitt S, Schrantee A, Sim K, Singh A, Stein F, Strike LT, van der Wee NJA, van der Werff SJA, Völzke H, Waltemate L, Whalley HC, Wittfeld K, Wright MJ, Yang TT, Zarate CA, Schmaal L, Rentería ME, ENIGMA-MDD Working Group

Default mode and salience network alterations in suicidal and non-suicidal self-injurious thoughts and behaviors in adolescents with depression.

Translational psychiatry

Ho TC, Walker JC, Teresi GI, Kulla A, Kirshenbaum JS, Gifuni AJ, Singh MK, Gotlib IH

Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders.

JAMA psychiatry

Patel Y, Parker N, Shin J, Howard D, French L, Thomopoulos SI, Pozzi E, Abe Y, Abé C, Anticevic A, Alda M, Aleman A, Alloza C, Alonso-Lana S, Ameis SH, Anagnostou E, McIntosh AA, Arango C, Arnold PD, Asherson P, Assogna F, Auzias G, Ayesa-Arriola R, Bakker G, Banaj N, Banaschewski T, Bandeira CE, Baranov A, Bargalló N, Bau CHD, Baumeister S, Baune BT, Bellgrove MA, Benedetti F, Bertolino A, Boedhoe PSW, Boks M, Bollettini I, Del Mar Bonnin C, Borgers T, Borgwardt S, Brandeis D, Brennan BP, Bruggemann JM, Bülow R, Busatto GF, Calderoni S, Calhoun VD, Calvo R, Canales-Rodríguez EJ, Cannon DM, Carr VJ, Cascella N, Cercignani M, Chaim-Avancini TM, Christakou A, Coghill D, Conzelmann A, Crespo-Facorro B, Cubillo AI, Cullen KR, Cupertino RB, Daly E, Dannlowski U, Davey CG, Denys D, Deruelle C, Di Giorgio A, Dickie EW, Dima D, Dohm K, Ehrlich S, Ely BA, Erwin-Grabner T, Ethofer T, Fair DA, Fallgatter AJ, Faraone SV, Fatjó-Vilas M, Fedor JM, Fitzgerald KD, Ford JM, Frodl T, Fu CHY, Fullerton JM, Gabel MC, Glahn DC, Roberts G, Gogberashvili T, Goikolea JM, Gotlib IH, Goya-Maldonado R, Grabe HJ, Green MJ, Grevet EH, Groenewold NA, Grotegerd D, Gruber O, Gruner P, Guerrero-Pedraza A, Gur RE, Gur RC, Haar S, Haarman BCM, Haavik J, Hahn T, Hajek T, Harrison BJ, Harrison NA, Hartman CA, Whalley HC, Heslenfeld DJ, Hibar DP, Hilland E, Hirano Y, Ho TC, Hoekstra PJ, Hoekstra L, Hohmann S, Hong LE, Höschl C, Høvik MF, Howells FM, Nenadic I, Jalbrzikowski M, James AC, Janssen J, Jaspers-Fayer F, Xu J, Jonassen R, Karkashadze G, King JA, Kircher T, Kirschner M, Koch K, Kochunov P, Kohls G, Konrad K, Krämer B, Krug A, Kuntsi J, Kwon JS, Landén M, Landrø NI, Lazaro L, Lebedeva IS, Leehr EJ, Lera-Miguel S, Lesch KP, Lochner C, Louza MR, Luna B, Lundervold AJ, MacMaster FP, Maglanoc LA, Malpas CB, Portella MJ, Marsh R, Martyn FM, Mataix-Cols D, Mathalon DH, McCarthy H, McDonald C, McPhilemey G, Meinert S, Menchón JM, Minuzzi L, Mitchell PB, Moreno C, Morgado P, Muratori F, Murphy CM, Murphy D, Mwangi B, Nabulsi L, Nakagawa A, Nakamae T, Namazova L, Narayanaswamy J, Jahanshad N, Nguyen DD, Nicolau R, O'Gorman Tuura RL, O'Hearn K, Oosterlaan J, Opel N, Ophoff RA, Oranje B, García de la Foz VO, Overs BJ, Paloyelis Y, Pantelis C, Parellada M, Pauli P, Picó-Pérez M, Picon FA, Piras F, Piras F, Plessen KJ, Pomarol-Clotet E, Preda A, Puig O, Quidé Y, Radua J, Ramos-Quiroga JA, Rasser PE, Rauer L, Reddy J, Redlich R, Reif A, Reneman L, Repple J, Retico A, Richarte V, Richter A, Rosa PGP, Rubia KK, Hashimoto R, Sacchet MD, Salvador R, Santonja J, Sarink K, Sarró S, Satterthwaite TD, Sawa A, Schall U, Schofield PR, Schrantee A, Seitz J, Serpa MH, Setién-Suero E, Shaw P, Shook D, Silk TJ, Sim K, Simon S, Simpson HB, Singh A, Skoch A, Skokauskas N, Soares JC, Soreni N, Soriano-Mas C, Spalletta G, Spaniel F, Lawrie SM, Stern ER, Stewart SE, Takayanagi Y, Temmingh HS, Tolin DF, Tomecek D, Tordesillas-Gutiérrez D, Tosetti M, Uhlmann A, van Amelsvoort T, van der Wee NJA, van der Werff SJA, van Haren NEM, van Wingen GA, Vance A, Vázquez-Bourgon J, Vecchio D, Venkatasubramanian G, Vieta E, Vilarroya O, Vives-Gilabert Y, Voineskos AN, Völzke H, von Polier GG, Walton E, Weickert TW, Weickert CS, Weideman AS, Wittfeld K, Wolf DH, Wu MJ, Yang TT, Yang K, Yoncheva Y, Yun JY, Cheng Y, Zanetti MV, Ziegler GC, Franke B, Hoogman M, Buitelaar JK, van Rooij D, Andreassen OA, Ching CRK, Veltman DJ, Schmaal L, Stein DJ, van den Heuvel OA, Turner JA, van Erp TGM, Pausova Z, Thompson PM, Paus T

Greater age-related changes in white matter morphometry following early life stress: Associations with internalizing problems in adolescence.

Developmental cognitive neuroscience

Chahal R, Kirshenbaum JS, Ho TC, Mastrovito D, Gotlib IH

Reduced anxiety and changes in amygdala network properties in adolescents with training for awareness, resilience, and action (TARA).

NeuroImage. Clinical

Tymofiyeva O, Henje E, Yuan JP, Huang CY, Connolly CG, Ho TC, Bhandari S, Parks KC, Sipes BS, Yang TT, Xu D

White-matter tract connecting anterior insula to nucleus accumbens predicts greater future motivation in adolescents.

Developmental cognitive neuroscience

Leong JK, Ho TC, Colich NL, Sisk L, Knutson B, Gotlib IH

Study Protocol for Teen Inflammation Glutamate Emotion Research (TIGER).

Frontiers in human neuroscience

Walker JC, Teresi GI, Weisenburger RL, Segarra JR, Ojha A, Kulla A, Sisk L, Gu M, Spielman DM, Rosenberg-Hasson Y, Maecker HT, Singh MK, Gotlib IH, Ho TC

Smaller caudate gray matter volume is associated with greater implicit suicidal ideation in depressed adolescents.

Journal of affective disorders

Ho TC, Teresi GI, Ojha A, Walker JC, Kirshenbaum JS, Singh MK, Gotlib IH

Higher Executive Control Network Coherence Buffers Against Puberty-Related Increases in Internalizing Symptoms During the COVID-19 Pandemic.

Biological psychiatry. Cognitive neuroscience and neuroimaging

Chahal R, Kirshenbaum JS, Miller JG, Ho TC, Gotlib IH

Early Life Stress, Frontoamygdala Connectivity, and Biological Aging in Adolescence: A Longitudinal Investigation.

Cerebral cortex (New York, N.Y. : 1991)

Miller JG, Ho TC, Humphreys KL, King LS, Foland-Ross LC, Colich NL, Ordaz SJ, Lin J, Gotlib IH

Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group.

Molecular psychiatry

Han LKM, Dinga R, Hahn T, Ching CRK, Eyler LT, Aftanas L, Aghajani M, Aleman A, Baune BT, Berger K, Brak I, Filho GB, Carballedo A, Connolly CG, Couvy-Duchesne B, Cullen KR, Dannlowski U, Davey CG, Dima D, Duran FLS, Enneking V, Filimonova E, Frenzel S, Frodl T, Fu CHY, Godlewska BR, Gotlib IH, Grabe HJ, Groenewold NA, Grotegerd D, Gruber O, Hall GB, Harrison BJ, Hatton SN, Hermesdorf M, Hickie IB, Ho TC, Hosten N, Jansen A, Kähler C, Kircher T, Klimes-Dougan B, Krämer B, Krug A, Lagopoulos J, Leenings R, MacMaster FP, MacQueen G, McIntosh A, McLellan Q, McMahon KL, Medland SE, Mueller BA, Mwangi B, Osipov E, Portella MJ, Pozzi E, Reneman L, Repple J, Rosa PGP, Sacchet MD, Sämann PG, Schnell K, Schrantee A, Simulionyte E, Soares JC, Sommer J, Stein DJ, Steinsträter O, Strike LT, Thomopoulos SI, van Tol MJ, Veer IM, Vermeiren RRJM, Walter H, van der Wee NJA, van der Werff SJA, Whalley H, Winter NR, Wittfeld K, Wright MJ, Wu MJ, Völzke H, Yang TT, Zannias V, de Zubicaray GI, Zunta-Soares GB, Abé C, Alda M, Andreassen OA, Bøen E, Bonnin CM, Canales-Rodriguez EJ, Cannon D, Caseras X, Chaim-Avancini TM, Elvsåshagen T, Favre P, Foley SF, Fullerton JM, Goikolea JM, Haarman BCM, Hajek T, Henry C, Houenou J, Howells FM, Ingvar M, Kuplicki R, Lafer B, Landén M, Machado-Vieira R, Malt UF, McDonald C, Mitchell PB, Nabulsi L, Otaduy MCG, Overs BJ, Polosan M, Pomarol-Clotet E, Radua J, Rive MM, Roberts G, Ruhe HG, Salvador R, Sarró S, Satterthwaite TD, Savitz J, Schene AH, Schofield PR, Serpa MH, Sim K, Soeiro-de-Souza MG, Sutherland AN, Temmingh HS, Timmons GM, Uhlmann A, Vieta E, Wolf DH, Zanetti MV, Jahanshad N, Thompson PM, Veltman DJ, Penninx BWJH, Marquand AF, Cole JH, Schmaal L

Biomarker Trends: Luminex & Olink, Dried Blood Spots & Plasma.

The Journal of Immunology

Yael Rosenberg-Hasson, Tiffany C. Ho, Tamara D. Simon, Jing Liang, Serena Chang, Iris Herschmann, Ian H. Gotlib, Holden T. Maecker

Subcortical shape alterations in major depressive disorder: Findings from the ENIGMA major depressive disorder working group.

Human brain mapping

Ho TC, Gutman B, Pozzi E, Grabe HJ, Hosten N, Wittfeld K, Völzke H, Baune B, Dannlowski U, Förster K, Grotegerd D, Redlich R, Jansen A, Kircher T, Krug A, Meinert S, Nenadic I, Opel N, Dinga R, Veltman DJ, Schnell K, Veer I, Walter H, Gotlib IH, Sacchet MD, Aleman A, Groenewold NA, Stein DJ, Li M, Walter M, Ching CRK, Jahanshad N, Ragothaman A, Isaev D, Zavaliangos-Petropulu A, Thompson PM, Sämann PG, Schmaal L

ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries.

Translational psychiatry

Thompson PM, Jahanshad N, Ching CRK, Salminen LE, Thomopoulos SI, Bright J, Baune BT, Bertolín S, Bralten J, Bruin WB, Bülow R, Chen J, Chye Y, Dannlowski U, de Kovel CGF, Donohoe G, Eyler LT, Faraone SV, Favre P, Filippi CA, Frodl T, Garijo D, Gil Y, Grabe HJ, Grasby KL, Hajek T, Han LKM, Hatton SN, Hilbert K, Ho TC, Holleran L, Homuth G, Hosten N, Houenou J, Ivanov I, Jia T, Kelly S, Klein M, Kwon JS, Laansma MA, Leerssen J, Lueken U, Nunes A, Neill JO, Opel N, Piras F, Piras F, Postema MC, Pozzi E, Shatokhina N, Soriano-Mas C, Spalletta G, Sun D, Teumer A, Tilot AK, Tozzi L, van der Merwe C, Van Someren EJW, van Wingen GA, Völzke H, Walton E, Wang L, Winkler AM, Wittfeld K, Wright MJ, Yun JY, Zhang G, Zhang-James Y, Adhikari BM, Agartz I, Aghajani M, Aleman A, Althoff RR, Altmann A, Andreassen OA, Baron DA, Bartnik-Olson BL, Marie Bas-Hoogendam J, Baskin-Sommers AR, Bearden CE, Berner LA, Boedhoe PSW, Brouwer RM, Buitelaar JK, Caeyenberghs K, Cecil CAM, Cohen RA, Cole JH, Conrod PJ, De Brito SA, de Zwarte SMC, Dennis EL, Desrivieres S, Dima D, Ehrlich S, Esopenko C, Fairchild G, Fisher SE, Fouche JP, Francks C, Frangou S, Franke B, Garavan HP, Glahn DC, Groenewold NA, Gurholt TP, Gutman BA, Hahn T, Harding IH, Hernaus D, Hibar DP, Hillary FG, Hoogman M, Hulshoff Pol HE, Jalbrzikowski M, Karkashadze GA, Klapwijk ET, Knickmeyer RC, Kochunov P, Koerte IK, Kong XZ, Liew SL, Lin AP, Logue MW, Luders E, Macciardi F, Mackey S, Mayer AR, McDonald CR, McMahon AB, Medland SE, Modinos G, Morey RA, Mueller SC, Mukherjee P, Namazova-Baranova L, Nir TM, Olsen A, Paschou P, Pine DS, Pizzagalli F, Rentería ME, Rohrer JD, Sämann PG, Schmaal L, Schumann G, Shiroishi MS, Sisodiya SM, Smit DJA, Sønderby IE, Stein DJ, Stein JL, Tahmasian M, Tate DF, Turner JA, van den Heuvel OA, van der Wee NJA, van der Werf YD, van Erp TGM, van Haren NEM, van Rooij D, van Velzen LS, Veer IM, Veltman DJ, Villalon-Reina JE, Walter H, Whelan CD, Wilde EA, Zarei M, Zelman V

Sex differences in the effects of gonadal hormones on white matter microstructure development in adolescence.

Developmental cognitive neuroscience

Ho TC, Colich NL, Sisk LM, Oskirko K, Jo B, Gotlib IH

White matter disturbances in major depressive disorder: a coordinated analysis across 20 international cohorts in the ENIGMA MDD working group.

Molecular psychiatry

van Velzen LS, Kelly S, Isaev D, Aleman A, Aftanas LI, Bauer J, Baune BT, Brak IV, Carballedo A, Connolly CG, Couvy-Duchesne B, Cullen KR, Danilenko KV, Dannlowski U, Enneking V, Filimonova E, Förster K, Frodl T, Gotlib IH, Groenewold NA, Grotegerd D, Harris MA, Hatton SN, Hawkins EL, Hickie IB, Ho TC, Jansen A, Kircher T, Klimes-Dougan B, Kochunov P, Krug A, Lagopoulos J, Lee R, Lett TA, Li M, MacMaster FP, Martin NG, McIntosh AM, McLellan Q, Meinert S, Nenadic I, Osipov E, Penninx BWJH, Portella MJ, Repple J, Roos A, Sacchet MD, Sämann PG, Schnell K, Shen X, Sim K, Stein DJ, van Tol MJ, Tomyshev AS, Tozzi L, Veer IM, Vermeiren R, Vives-Gilabert Y, Walter H, Walter M, van der Wee NJA, van der Werff SJA, Schreiner MW, Whalley HC, Wright MJ, Yang TT, Zhu A, Veltman DJ, Thompson PM, Jahanshad N, Schmaal L

No Alterations of Brain Structural Asymmetry in Major Depressive Disorder: An ENIGMA Consortium Analysis.

The American journal of psychiatry

de Kovel CGF, Aftanas L, Aleman A, Alexander-Bloch AF, Baune BT, Brack I, Bülow R, Busatto Filho G, Carballedo A, Connolly CG, Cullen KR, Dannlowski U, Davey CG, Dima D, Dohm K, Erwin-Grabner T, Frodl T, Fu CHY, Hall GB, Glahn DC, Godlewska B, Gotlib IH, Goya-Maldonado R, Grabe HJ, Groenewold NA, Grotegerd D, Gruber O, Harris MA, Harrison BJ, Hatton SN, Hickie IB, Ho TC, Jahanshad N, Kircher T, Krämer B, Krug A, Lagopoulos J, Leehr EJ, Li M, MacMaster FP, MacQueen G, McIntosh AM, McLellan Q, Medland SE, Mueller BA, Nenadic I, Osipov E, Papmeyer M, Portella MJ, Reneman L, Rosa PGP, Sacchet MD, Schnell K, Schrantee A, Sim K, Simulionyte E, Sindermann L, Singh A, Stein DJ, Ubani BN, Van der Wee NJA, Van der Werff SJA, Veer IM, Vives-Gilabert Y, Völzke H, Walter H, Walter M, Schreiner MW, Whalley H, Winter N, Wittfeld K, Yang TT, Yüksel D, Zaremba D, Thompson PM, Veltman DJ, Schmaal L, Francks C

Interactive impact of childhood maltreatment, depression, and age on cortical brain structure: mega-analytic findings from a large multi-site cohort.

Psychological medicine

Tozzi L, Garczarek L, Janowitz D, Stein DJ, Wittfeld K, Dobrowolny H, Lagopoulos J, Hatton SN, Hickie IB, Carballedo A, Brooks SJ, Vuletic D, Uhlmann A, Veer IM, Walter H, Bülow R, Völzke H, Klinger-König J, Schnell K, Schoepf D, Grotegerd D, Opel N, Dannlowski U, Kugel H, Schramm E, Konrad C, Kircher T, Jüksel D, Nenadic I, Krug A, Hahn T, Steinsträter O, Redlich R, Zaremba D, Zurowski B, Fu CHY, Dima D, Cole J, Grabe HJ, Connolly CG, Yang TT, Ho TC, LeWinn KZ, Li M, Groenewold NA, Salminen LE, Walter M, Simmons AN, van Erp TGM, Jahanshad N, Baune BT, van der Wee NJA, van Tol MJ, Penninx BWJH, Hibar DP, Thompson PM, Veltman DJ, Schmaal L, Frodl T

Early life stress, cortisol, frontolimbic connectivity, and depressive symptoms during puberty.

Development and psychopathology

Kircanski K, Sisk LM, Ho TC, Humphreys KL, King LS, Colich NL, Ordaz SJ, Gotlib IH

241. Sensitive Periods of Stress and Adolescent Amygdala–Ventromedial Prefrontal Cortex Connectivity: A Longitudinal Investigation.

Biological psychiatry

Tiffany Ho, Kathryn Humphreys, Lucy King, Natalie Colich, Jaclyn Schwartz, Kyoko Ohashi, Martin Teicher, Ian Gotlib

F99. Higher Levels of Inflammatory Proteins are Associated With Reduced White Matter Integrity in Depressed Adolescents.

Biological psychiatry

Lucinda Sisk, Artenisa Kulla, Yael Rosenberg-Hasson, Holden Maecker, Ian Gotlib, Tiffany Ho

Anxiety and Attentional Bias in Children with Specific Learning Disorders.

Journal of abnormal child psychology

Haft SL, Duong PH, Ho TC, Hendren RL, Hoeft F

Resting-state functional connectivity and inflexibility of daily emotions in major depression.

Journal of affective disorders

Schwartz J, Ordaz SJ, Kircanski K, Ho TC, Davis EG, Camacho MC, Gotlib IH

Factors That Influence Student Choice in Family Medicine A National Focus Group.

Family medicine

Alavi M, Ho T, Stisher C, Richardson E, Kelly C, McCrory K, Snellings J, Zurek K, Boltz MW

Evidence for a sensitive period in the effects of early life stress on hippocampal volume.

Developmental science

Humphreys KL, King LS, Sacchet MD, Camacho MC, Colich NL, Ordaz SJ, Ho TC, Gotlib IH

Test-Retest Reliability of Graph Theoretic Metrics in Adolescent Brains.

Brain connectivity

Yuan JP, Henje Blom E, Flynn T, Chen Y, Ho TC, Connolly CG, Dumont Walter RA, Yang TT, Xu D, Tymofiyeva O

Reward-circuit biomarkers of risk and resilience in adolescent depression.

Journal of affective disorders

Fischer AS, Ellwood-Lowe ME, Colich NL, Cichocki A, Ho TC, Gotlib IH

Reduced dorsal striatal gray matter volume predicts implicit suicidal ideation in adolescents.

Social cognitive and affective neuroscience

Ho TC, Cichocki AC, Gifuni AJ, Catalina Camacho M, Ordaz SJ, Singh MK, Gotlib IH

An exploratory examination of reappraisal success in depressed adolescents: Preliminary evidence of functional differences in cognitive control brain regions.

Journal of affective disorders

LeWinn KZ, Strigo IA, Connolly CG, Ho TC, Tymofiyeva O, Sacchet MD, Weng HY, Blom EH, Simmons AN, Yang TT

Network-based approaches to examining stress in the adolescent brain.

Neurobiology of stress

Ho TC, Dennis EL, Thompson PM, Gotlib IH

200. Differing Windows of Sensitivity to Stress in Amygdala-Ventromedial Prefrontal Cortex Structural and Functional Connectivity: Implications for the Neurobiology of Depression in Youth.

Biological psychiatry

Tiffany Ho, Kathryn Humphreys, Lucy King, Natalie Colich, Jaclyn Schwartz, Josiah Leong, Kyoko Ohashi, Martin Teicher, Ian Gotlib

Neural Markers of Resilience in Adolescent Females at Familial Risk for Major Depressive Disorder.

JAMA psychiatry

Fischer AS, Camacho MC, Ho TC, Whitfield-Gabrieli S, Gotlib IH

High levels of mitochondrial DNA are associated with adolescent brain structural hypoconnectivity and increased anxiety but not depression.

Journal of affective disorders

Tymofiyeva O, Henje Blom E, Ho TC, Connolly CG, Lindqvist D, Wolkowitz OM, Lin J, LeWinn KZ, Sacchet MD, Han LKM, Yuan JP, Bhandari SP, Xu D, Yang TT

The association between early life stress and prefrontal cortex activation during implicit emotion regulation is moderated by sex in early adolescence.

Development and psychopathology

Colich NL, Williams ES, Ho TC, King LS, Humphreys KL, Price AN, Ordaz SJ, Gotlib IH

Toward an Improved Understanding of Corticobasal Ganglia Reward Circuitry in Adolescent Depression.

Biological psychiatry. Cognitive neuroscience and neuroimaging

Ho TC, Auerbach RP

Network basis of suicidal ideation in depressed adolescents.

Journal of affective disorders

Ordaz SJ, Goyer MS, Ho TC, Singh MK, Gotlib IH

Effects of sensitivity to life stress on uncinate fasciculus segments in early adolescence.

Social cognitive and affective neuroscience

Ho TC, King LS, Leong JK, Colich NL, Humphreys KL, Ordaz SJ, Gotlib IH

Like mother like daughter: putamen activation as a mechanism underlying intergenerational risk for depression.

Social cognitive and affective neuroscience

Colich NL, Ho TC, Ellwood-Lowe ME, Foland-Ross LC, Sacchet MD, LeMoult JL, Gotlib IH

Hyperactivation in Cognitive Control and Visual Attention Brain Regions During Emotional Interference in Adolescent Depression.

Biological psychiatry. Cognitive neuroscience and neuroimaging

Colich NL, Ho TC, Foland-Ross LC, Eggleston C, Ordaz SJ, Singh MK, Gotlib IH

Inflexible Functional Connectivity of the Dorsal Anterior Cingulate Cortex in Adolescent Major Depressive Disorder.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Ho TC, Sacchet MD, Connolly CG, Margulies DS, Tymofiyeva O, Paulus MP, Simmons AN, Gotlib IH, Yang TT

Feasibility and Preliminary Efficacy of a Novel RDoC-Based Treatment Program for Adolescent Depression: "Training for Awareness Resilience and Action" (TARA)-A Pilot Study.

Frontiers in psychiatry

Henje Blom E, Tymofiyeva O, Chesney MA, Ho TC, Moran P, Connolly CG, Duncan LG, Baldini L, Weng HY, Acree M, Goldman V, Hecht FM, Yang TT

Resting-state functional connectivity of the amygdala and longitudinal changes in depression severity in adolescent depression.

Journal of affective disorders

Connolly CG, Ho TC, Blom EH, LeWinn KZ, Sacchet MD, Tymofiyeva O, Simmons AN, Yang TT

DTI-based connectome analysis of adolescents with major depressive disorder reveals hypoconnectivity of the right caudate.

Journal of affective disorders

Tymofiyeva O, Connolly CG, Ho TC, Sacchet MD, Henje Blom E, LeWinn KZ, Xu D, Yang TT

Intergenerational Neuroimaging of Human Brain Circuitry.

Trends in neurosciences

Ho TC, Sanders SJ, Gotlib IH, Hoeft F

Large-Scale Hypoconnectivity Between Resting-State Functional Networks in Unmedicated Adolescent Major Depressive Disorder.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Sacchet MD, Ho TC, Connolly CG, Tymofiyeva O, Lewinn KZ, Han LK, Blom EH, Tapert SF, Max JE, Frank GK, Paulus MP, Simmons AN, Gotlib IH, Yang TT

Fusiform Gyrus Dysfunction is Associated with Perceptual Processing Efficiency to Emotional Faces in Adolescent Depression: A Model-Based Approach.

Frontiers in psychology

Ho TC, Zhang S, Sacchet MD, Weng H, Connolly CG, Henje Blom E, Han LK, Mobayed NO, Yang TT

The neuroscience and context of adolescent depression.

Acta paediatrica (Oslo, Norway : 1992)

Henje Blom E, Ho TC, Connolly CG, LeWinn KZ, Sacchet MD, Tymofiyeva O, Weng HY, Yang TT

Peripheral telomere length and hippocampal volume in adolescents with major depressive disorder.

Translational psychiatry

Henje Blom E, Han LK, Connolly CG, Ho TC, Lin J, LeWinn KZ, Simmons AN, Sacchet MD, Mobayed N, Luna ME, Paulus M, Epel ES, Blackburn EH, Wolkowitz OM, Yang TT

Altered insular activation and increased insular functional connectivity during sad and happy face processing in adolescent major depressive disorder.

Journal of affective disorders

Henje Blom E, Connolly CG, Ho TC, LeWinn KZ, Mobayed N, Han L, Paulus MP, Wu J, Simmons AN, Yang TT

Emotion-Dependent Functional Connectivity of the Default Mode Network in Adolescent Depression.

Biological psychiatry

Ho TC, Connolly CG, Henje Blom E, LeWinn KZ, Strigo IA, Paulus MP, Frank G, Max JE, Wu J, Chan M, Tapert SF, Simmons AN, Yang TT

The development of an RDoC-based treatment program for adolescent depression: "Training for Awareness, Resilience, and Action" (TARA).

Frontiers in human neuroscience

Henje Blom E, Duncan LG, Ho TC, Connolly CG, LeWinn KZ, Chesney M, Hecht FM, Yang TT

White matter correlates of adolescent depression: structural evidence for frontolimbic disconnectivity.

Journal of the American Academy of Child and Adolescent Psychiatry

LeWinn KZ, Connolly CG, Wu J, Drahos M, Hoeft F, Ho TC, Simmons AN, Yang TT

Functional connectivity of negative emotional processing in adolescent depression.

Journal of affective disorders

Ho TC, Yang G, Wu J, Cassey P, Brown SD, Hoang N, Chan M, Connolly CG, Henje-Blom E, Duncan LG, Chesney MA, Paulus MP, Max JE, Patel R, Simmons AN, Yang TT

Resting-state functional connectivity of subgenual anterior cingulate cortex in depressed adolescents.

Biological psychiatry

Connolly CG, Wu J, Ho TC, Hoeft F, Wolkowitz O, Eisendrath S, Frank G, Hendren R, Max JE, Paulus MP, Tapert SF, Banerjee D, Simmons AN, Yang TT

Altered cerebral perfusion in executive, affective, and motor networks during adolescent depression.

Journal of the American Academy of Child and Adolescent Psychiatry

Ho TC, Wu J, Shin DD, Liu TT, Tapert SF, Yang G, Connolly CG, Frank GK, Max JE, Wolkowitz O, Eisendrath S, Hoeft F, Banerjee D, Hood K, Hendren RL, Paulus MP, Simmons AN, Yang TT

Target enhancement and distractor suppression in naturalistic visual search.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Ho TC, Ester EF

Perceptual consequences of feature-based attentional enhancement and suppression.

Journal of vision

Ho TC, Brown S, Abuyo NA, Ku EH, Serences JT

Evidence TRPV4 contributes to mechanosensitive ion channels in mouse skeletal muscle fibers.

Channels (Austin, Tex.)

Ho TC, Horn NA, Huynh T, Kelava L, Lansman JB

The optimality of sensory processing during the speed-accuracy tradeoff.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Ho T, Brown S, van Maanen L, Forstmann BU, Wagenmakers EJ, Serences JT

Neural correlates of trial-to-trial fluctuations in response caution.

The Journal of neuroscience : the official journal of the Society for Neuroscience

van Maanen L, Brown SD, Eichele T, Wagenmakers EJ, Ho T, Serences J, Forstmann BU

Domain general mechanisms of perceptual decision making in human cortex.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Ho TC, Brown S, Serences JT